SNAKE – An ion microbeam for biomedical research
Venerdì 29 novembre 2019, alle ore 11.00 in aula 1G09
la prof.ssa Judith Reindl, Institut für angewandte Physik und Messtechnik, Universität der Bundeswehr München,
terrà un seminario dal titolo:
"SNAKE – An ion microbeam for biomedical research"
The influence of ionizing radiation on living organism is subject of ongoing research. In particular, the effect of low doses of radiation is widely unknown. One approach is to irradiate and analyze living cells in culture. Using modern techniques from molecular biology, it is possible to study the radiation-induced damages in the cell (e.g. DNA double-strand breaks) as well as the involved repair proteins on a microscopic scale.
Among all ionizing radiations, highly energetic ions are particularly suitable for the irradiation of living cells. The ion microprobe SNAKE (Superconducting nanoprobe for applied nuclear physics experiments) is installed at the 14 MV Tandem Accelerator in Garching near Munich and can be used for material analysis as well as for radiation biology research. The sub-micrometer beam size allows the targeted irradiation of single defined cells but also of more complex samples with single or counted ions, making it a suitable tool for low and high dose research. This talk will give an overview on the various studies performed at SNAKE ranging from principle studies regarding DNA repair within high- and low-LET particle induced damage up to pre-clinical studies on the modern radiotherapy methods - proton minibeam therapy and FLASH therapy.